The ADI, or Acceptable Daily Intake, indicates the quantity of a substance that a person of a given weight can consume every day for the rest of their life without risk to health. This limit is calculated by health and food safety experts on the basis of numerous scientific studies. The ADI is generally expressed in milligrams (mg) of substance per kilogramme (kg) of body weight per day. A number of public health authorities around the world have the role of establishing ADIs to protect populations. These include the World Health Organisation (WHO) at international level, the European Food Safety Authority (EFSA) in Europe, and the Food and Drug Administration (FDA) in the United States. The studies taken into account sometimes differ from one authority to another, which explains the existence of multiple ADIs for certain additives.