Quali sono le principali fonti scientifiche per valutare gli additivi?

Abd-Elhakim YM, Moustafa GG, Hashem MM, Ali HA, Abo-El-Sooud K, El-Metwally AE. (2019). Influence of the long-term exposure to tartrazine and chlorophyll on the fibrogenic signalling pathway in liver and kidney of rats: the expression patterns of collagen 1-alpha, TGFbeta-1, fibronectin, and caspase-3 genes. Environ Sci Pollut Res Int 26:12368-12378. https://pubmed.ncbi.nlm.nih.gov/30847814/

Abd-Elhakim, Y.M., Behairy, A., Hashem, M.M.M. et al. Toll-like receptors and nuclear factor kappa B signaling pathway involvement in hepatorenal oxidative damage induced by some food preservatives in rats. Sci Rep 13, 5938 (2023). https://doi.org/10.1038/s41598-023-32887-9

Acero et al., 1998. Occupational asthma and food allergy due to Carmine. Allergy, 53, 897–901.

Adler GK, Hornik ES, Murray G, Bhandari S, Yadav Y, Heydarpour M, Basu R, Garg R, Tirosh A. Acute effects of the food preservative propionic acid on glucose metabolism in humans. BMJ Open Diabetes Res Care. 2021 Jul;9(1):e002336.

Aguayo-Guerrero JA, Méndez-García LA, Manjarrez-Reyna AN, Esquivel-Velázquez M, León-Cabrera S, Meléndez G, Zambrano E, Ramos-Martínez E, Fragoso JM, Briones-Garduño JC, Escobedo G (2023). Newborns from Mothers Who Intensely Consumed Sucralose during Pregnancy Are Heavier and Exhibit Markers of Metabolic Alteration and Low-Grade Systemic Inflammation: A Cross-Sectional, Prospective Study. Biomedicines. 2023 Feb 21;11(3):650. doi: 10.3390/biomedicines11030650. PMID: 36979631; PMCID: PMC10045555. https://pubmed.ncbi.nlm.nih.gov/36979631/

Ahangari H, Bahramian B, Khezerlou A, Tavassoli M, Kiani-Salmi N, Tarhriz V, Ehsani A. Association between monosodium glutamate consumption with changes in gut microbiota and related metabolic dysbiosis-A systematic review. Food Sci Nutr. 2024 Apr 29;12(8):5285-5295. doi: 10.1002/fsn3.4198. PMID: 39139924; PMCID: PMC11317663. https://onlinelibrary.wiley.com/doi/10.1002/fsn3.4198

Ali Noorafshan, Maedeh Hashemi, Saied Karbalay-Doust, Fatemeh Karimi, High dose Allura Red, rather than the ADI dose, induces structural and behavioral changes in the medial prefrontal cortex of rats and taurine can protect it, Acta Histochemica, Volume 120, Issue 6, 2018 https://doi.org/10.1016/j.acthis.2018.07.004

Ali, M. Y., Hassan, G. M., Hassan, A. M. S., Mohamed, Z. A., & Ramadan, M. F. (2019). In vivo genotoxicity assessment of sunset yellow and sodium benzoate in female rats. Drug and chemical toxicology, 1-10. https://pubmed.ncbi.nlm.nih.gov/30208729/

Alofe O, Kisanga E, Inayat-Hussain SH, Fukumura M, Garcia-Milian R, Perera L, Vasiliou V, Whirledge S (2019). Determining the endocrine disruption potential of industrial chemicals using an integrative approach: Public databases, in vitro exposure, and modeling receptor interactions. Environ Int. 2019 Oct;131:104969. doi: 10.1016/j.envint.2019.104969. Epub 2019 Jul 13. PMID: 31310931; PMCID: PMC6728168. https://pubmed.ncbi.nlm.nih.gov/31310931/

Amadasi A, Mozzarelli A, Meda C, Maggi A and Cozzini P, 2009. Identification of Xenoestrogens in Food Additives by an Integrated in Silico and in vitro Approach. Chemical Research in Toxicology, 22, 52-63 https://pubmed.ncbi.nlm.nih.gov/19063592/

American Society of Health-System Pharmacists 2014; Book Drug Information 2014. Bethesda, MD. 2014, p. 2777\n

Amin KA, Abdel Hameid H, Abd Elsttar AH. Effect of food azo dyes tartrazine and carmoisine on biochemical parameters related to renal, hepatic function and oxidative stress biomarkers in young male rats. Food Chem Toxicol 2010; 48: 2994–2999. https://pubmed.ncbi.nlm.nih.gov/20678534/

Anbara, H., Kian, M., Darya, G. H., & Sheibani, M. T. (2022). Long‐term intake of aspartame‐induced cardiovascular toxicity is reflected in altered histochemical parameters, evokes oxidative stress, and trigger P53‐dependent apoptosis in a mouse model. International Journal of Experimental Pathology, 103(6), 252-262. https://doi.org/10.1111/iep.12458

Anbara, H., Sheibani, M. T., & Razi, M. (2020). Long-term effect of aspartame on male reproductive system: Evidence for testicular histomorphometrics, Hsp70-2 protein expression and biochemical status. International journal of fertility & sterility, 14(2), 91. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7382684/

Anbara, H., Sheibani, M. T., Razi, M., & Kian, M. (2021). Insight into the mechanism of aspartame‐induced toxicity in male reproductive system following long‐term consumption in mice model. Environmental toxicology, 36(2), 223-237. https://doi.org/10.1002/tox.23028

ANSES, 2005. Opinion of the Scientific Panel on Food Additives, Flavourings, Processing Aids and Materials in Contact with Food on a request from the Commission related to Semicarbazide in foods (2005) https://efsa.onlinelibrary.wiley.com/doi/pdf/10.2903/j.efsa.2005.219

ANSES, 2008. Evaluation des risques sanitaires liés au dépassement des limites de qualité des bromates dans les eaux destinées à la consommation humaine. https://www.anses.fr/fr/content/fiche-20-evaluation-des-risques-sanitaires-lies-au-depassement-des-limites-de-qualite-des-0

ANSES, 2011. Étude de l’alimentation totale française 2 (EAT 2) Tome 2 - Résidus de pesticides, additifs, acrylamide, hydrocarbures aromatiques polycycliques. https://www.anses.fr/fr/system/files/PASER2006sa0361Ra2.pdf

ANSES, 2013. Avis de l'Anses en réponse à la consultation de l'Autorité Européenne de sécurité des aliments sur son projet d'avis concernant la réévaluation de l'aspartame (E951) en tant qu'additif alimentaire. Saisine n° 2013-SA-0016. https://www.anses.fr/fr/system/files/ERCA2013sa0016.pdf

ANSES, 2014. Foodborne exposure to aluminium https://www.anses.fr/en/content/foodborne-exposure-aluminium

ANSES, 2015. Avis du 19 novembre 2014 révisé le 9 janvier 2015 relatif à l’évaluation des bénéfices et des risques nutritionnels des édulcorants intenses. Saisine n°2011-SA-0161. https://www.anses.fr/fr/system/files/NUT2011sa0161Ra.pdf

ANSES, 2015. Avis relatif à l’évaluation des apports en vitamines et minéraux issus de l'alimentation non enrichie, de l’alimentation enrichie et des compléments alimentaires dans la population française : estimation des apports usuels, des prévalences d'inadéquation et des risques de dépassement des limites de sécurité. Saisine n°2012-SA-0142. https://www.anses.fr/fr/content/avis-de-lanses-relatif-%C3%A0-l%E2%80%99%C3%A9valuation-des-apports-en-vitamines-et-min%C3%A9raux-issus-de

ANSES, 2016. Avis sur les perturbateurs endocriniens (SNPE): l’ATBC (acétylcitrate de tributyle(n°CAS 77-90-7), le TBC (citratede tributyle, n° CAS 77-94-1), le BHT (hydroxytoluene butylé, n°CAS 128-37-0), l’acide téréphtalique (n° CAS 100-21-0), le méthyl salicylate (n°CAS 119-36-8) et l’iprodione (n° CAS 36734-19-7). https://www.anses.fr/fr/system/files/REACH2016RE0001.pdf

ANSES, 2017. Avis relatif à l’exposition alimentaire aux nanoparticules de dioxyde de titane.

ANSES, 2019. Avis de l’Agence nationale de sécurité sanitaire de l’alimentation, de l’environnement et du travail relatif aux risques liés à l’ingestion de l’additif alimentaire E171.

ANSES, 2020. Collective expert report: Nanomaterials in food product https://www.anses.fr/en/content/nanomaterials-food-ansess-recommendations-improving-their-identification-and-better

ANSES, 2020. Rapport d’expertise collective, mai 2020. Nanomatériaux dans les produits destinés à l’alimentation. https://www.anses.fr/fr/system/files/ERCA2016SA0226Ra.pdf

ANSES, 2021. ANSES OPINION on a specific health risk assessment guide for nanomaterials in food products https://www.anses.fr/en/system/files/ERCA2016SA0226EN.pdf

ANSES, 2022. Évaluation des risques liés à la consommation de nitrates et nitrites. https://www.anses.fr/fr/content/r%C3%A9duire-l%E2%80%99exposition-aux-nitrites-et-aux-nitrates-dans-l%E2%80%99alimentation

Aouey et al. Silica Nanoparticles Induce Hepatotoxicity by Triggering Oxidative Damage, Apoptosis, and Bax-Bcl2 Signaling Pathway. Biol Trace Elem Res. 2021 Jun 10.

Arnold et al., 2012. Artificial food colors and attention-deficit/hyperactivity symptoms: conclusions to dye for. Neurotherapeutics, 9(3), 599-609. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3441937/

Azad et al., 2017. Nonnutritive sweeteners and cardiometabolic health : a systematic review and meta-analysis of randomized controlled trials and prospective cohort studies. Cmaj, 189(28), E929-E939. https://www.ncbi.nlm.nih.gov/pubmed/28716847

Azad, M. B., Archibald, A., Tomczyk, M. M., Head, A., Cheung, K. G., de Souza, R. J., ... & Dolinsky, V. W. (2020). Nonnutritive sweetener consumption during pregnancy, adiposity, and adipocyte differentiation in offspring: evidence from humans, mice, and cells. International Journal of Obesity, 44(10), 2137-2148. https://doi.org/10.1038/s41366-020-0575-x

Baad‐Hansen et al. Effect of systemic monosodium glutamate (MSG) on headache and pericranial muscle sensitivity. Cephalalgia. 2010 Jan;30(1):68-76.

Baldwin JL, Chou AH and Solomon WR, 1997. Popsicle-induced anaphylaxis due to Carmine dye allergy. Annals of Allergy, Asthma and Immunology, 79, 415–419.

Bandyopadhyay, A., Ghoshal, S., & Mukherjee, A. (2008). Genotoxicity testing of low-calorie sweeteners: aspartame, acesulfame-K, and saccharin. Drug and chemical toxicology, 31(4), 447-457. https://doi.org/10.1080/01480540802390270

Barakat, H.; Al-Roug, K.; Algonaiman, R.; Althwab, S.A.; Alfheeaid, H.A.; Alhomaid, R.M.; Almujaydil, M.S.; Bushnaq, T.; Ebeid, T.A (2023). Biological Assessment of Stevioside and Sucralose as Sucrose Substitutes for Diabetics on STZ-Induced Diabetes in Rats. Molecules 2023, 28, 940. https://doi.org/10.3390/molecules28030940

Barciela, P., Perez-Vazquez, A., & Prieto, M. A. (2023). Azo dyes in the food industry: Features, classification, toxicity, alternatives, and regulation. Food and Chemical Toxicology, 178. https://doi.org/10.1016/j.fct.2023.113935

Beards, E., Tuohy, K., & Gibson, G. (2010). A human volunteer study to assess the impact of confectionery sweeteners on the gut microbiota composition. British Journal of Nutrition, 104(5), 701-708.

Becker, S. L., Chiang, E., Plantinga, A., Carey, H. V., Suen, G., & Swoap, S. J. (2020). Effect of stevia on the gut microbiota and glucose tolerance in a murine model of diet-induced obesity. FEMS microbiology ecology, 96(6), fiaa079. https://doi.org/10.1093/femsec/fiaa079

Beezhold, B. L., Johnston, C. S., & Nochta, K. A. (2014). Sodium benzoate–rich beverage consumption is associated with increased reporting of ADHD symptoms in college students: A pilot investigation. Journal of attention disorders, 18(3), 236-241. https://pubmed.ncbi.nlm.nih.gov/22538314/

Benard, Claudine et al. “Degraded carrageenan causing colitis in rats induces TNF secretion and ICAM-1 upregulation in monocytes through NF-kappaB activation” PloS one vol. 5,1 e8666. 13 Jan. 2010. https://pmc.ncbi.nlm.nih.gov/articles/PMC2800179/

Bendig, P., Maier, L., & Vetter, W. (2012). Brominated vegetable oil in soft drinks–an underrated source of human organobromine intake. Food chemistry, 133(3), 678-682.

Bettini, S., Boutet-Robinet, E., Cartier, C., Coméra, C., Gaultier, E., Dupuy, J., ... & Thieriet, N. (2017). Food-grade TiO 2 impairs intestinal and systemic immune homeostasis, initiates preneoplastic lesions and promotes aberrant crypt development in the rat colon. Scientific Reports, 7, 40373.

BFR, 2019. Reducing aluminium intake can minimise potential health risks. https://www.bfr.bund.de/en/press_information/2019/45/reducing_aluminium_intake_can_minimise_potential_health_risks-243396.html

Bhattacharyya S, O-Sullivan I, Katyal S, Unterman T, Tobacman JK. Exposure to the common food additive carrageenan leads to glucose intolerance, insulin resistance and inhibition of insulin signalling in HepG2 cells and C57BL/6J mice. Diabetologia. 2012 Jan;55(1):194-203. https://pubmed.ncbi.nlm.nih.gov/22011715/

Bian et al., 2017. The artificial sweetener acesulfame potassium affects the gut microbiome and body weight gain in CD-1 mice. PLoS One, 12(6), e0178426. https://pubmed.ncbi.nlm.nih.gov/28594855/

Bian X., Tu P., Chi L., Gao B., Ru H., Lu K. Saccharin induced liver inflammation in mice by altering the gut microbiota and its metabolic functions. Food Chem. Toxicol. 2017;107:530–539. https://www.sciencedirect.com/science/article/abs/pii/S0278691517302235

Bian, X., Chi, L., Gao, B., Tu, P., Ru, H., & Lu, K. (2017). Gut microbiome response to sucralose and its potential role in inducing liver inflammation in mice. Frontiers in physiology, 8, 487. - https://doi.org/10.3389/fphys.2017.00487

Bianchi MG, Chiu M, Taurino G, Bergamaschi E, Turroni F, Mancabelli L, Longhi G, Ventura M, Bussolati O. Amorphous silica nanoparticles and the human gut microbiota: a relationship with multiple implications. J Nanobiotechnology. (2024) Jan 30;22(1):45. doi: 10.1186/s12951-024-02305-x. PMID: 38291460; PMCID: PMC10826219. https://pubmed.ncbi.nlm.nih.gov/38291460/

Bondy, S. C. The Neurotoxicity of Environmental Aluminum Is Still an Issue. Neurotoxicology 2010, 31 (5), 575–581.

Boonnate et al., 2015. Monosodium glutamate dietary consumption decreases pancreatic β-cell mass in adult Wistar rats. PLoS One, 10(6), e0131595.

Bornemann, V., Werness, S. C., Buslinger, L., & Schiffman, S. S. (2018). Intestinal metabolism and bioaccumulation of sucralose in adipose tissue in the rat. Journal of Toxicology and Environmental Health, Part A. https://doi.org/10.1080/15287394.2018.1502560

Brand, W., van Kesteren, P. C. E., Peters, R. J. B., & Oomen, A. G. (2021). Issues currently complicating the risk assessment of synthetic amorphous silica (SAS) nanoparticles after oral exposure. Nanotoxicology, 15(7), 905–933. https://doi.org/10.1080/17435390.2021.1931724

Bridge-Comer, P. E., Vickers, M. H., Morton-Jones, J., Spada, A., Rong, J., & Reynolds, C. M. (2021). Impact of maternal intake of artificial sweetener, Acesulfame-K, on metabolic and reproductive health outcomes in male and female mouse offspring. Frontiers in Nutrition, 8. https://doi.org/10.3389/fnut.2021.745203

Bridge-Comer, P. E., Vickers, M. H., Morton-Jones, J., Spada, A., Rong, J., & Reynolds, C. M. (2022). Maternal intake of fructose or artificial sweetener during pregnancy and lactation has persistent effects on metabolic and reproductive health of dams post-weaning. Journal of Developmental Origins of Health and Disease, 1-8. https://doi.org/10.1017/S2040174422000022

Bueno-Hernández, N., Esquivel-Velázquez, M., Alcántara-Suárez, R., Gómez-Arauz, A. Y., Espinosa-Flores, A. J., de León-Barrera, K. L., ... & Meléndez, G. (2020). Chronic sucralose consumption induces elevation of serum insulin in young healthy adults: a randomized, double blind, controlled trial. Nutrition journal, 19(1), 1-12. https://doi.org/10.1186/s12937-020-00549-5

Bursley, J. K., & Rockwell, C. E. (2020). Nrf2-dependent and-independent effects of tBHQ in activated murine B cells. Food and Chemical Toxicology, 145, 111595.

Çadirci, K., Tozlu, Ö. Ö., Türkez, H., & Mardinoğlu, A. (2020). The in vitro cytotoxic, genotoxic, and oxidative damage potentials of the oral artificialsweetener aspartame on cultured human blood cells. Turkish Journal of Medical Sciences, 50(2), 448-454. https://pubmed.ncbi.nlm.nih.gov/32222132/

California State Assembly. (2024). AB 2316: Pupil nutrition: substances: prohibition (Chapter 914). California Legislative Information. https://leginfo.legislature.ca.gov/faces/billNavClient.xhtml?bill_id=202320240AB2316

Calvo MS, Dunford EK, Uribarri J (2023). Industrial Use of Phosphate Food Additives: A Mechanism Linking Ultra-Processed Food Intake to Cardiorenal Disease Risk? Nutrients. 2023 Aug 9;15(16):3510. doi: 10.3390/nu15163510. PMID: 37630701; PMCID: PMC10459924. https://pubmed.ncbi.nlm.nih.gov/37630701/

Calvo MS, Tucker KL, 2013. Is phosphorus intake that exceeds dietary requirements a risk factor in bone health? Ann N Y Acad Sci. 2013 Oct;1301:29-35. https://pubmed.ncbi.nlm.nih.gov/24472074/

Calvo MS, Uribarri J, 2013. Public health impact of dietary phosphorus excess on bone and cardiovascular health in the general population. Am J Clin Nutr. 2013 Jul;98(1):6-15. doi: 10.3945/ajcn.112.053934. Epub 2013 May 29. https://pubmed.ncbi.nlm.nih.gov/23719553/

Calvo, M. S., Sherman, R. A., & Uribarri, J. (2019). Dietary Phosphate and the Forgotten Kidney Patient: A Critical Need for FDA Regulatory Action. American Journal of Kidney Diseases, 73(4), 542–551. https://doi.org/10.1053/j.ajkd.2018.11.004

Carocho, M., Morales, P., & Ferreira, I. C. (2017). Sweeteners as food additives in the XXI century: A review of what is known, and what is to come. Food and Chemical Toxicology, 107, 302-317. https://pubmed.ncbi.nlm.nih.gov/28689062/

Cecchin, Mireille. \Domaines d'application des sucroesters et sucroglycérides.\ Rapport de recherche bibliographique. DESS Ingénierie Documentaire, ENSSIB, Université Claude Bernard Lyon 1, 2000-2001, sous la direction de Melle Gagnaire, Mr Bouchu, Mr Queneau. Laboratoire de sucrochimie CNRS-BEGHIN-SAY, Villeurbanne. http://enssibal.enssib.fr/bibliotheque/documents/dessid/rrbcecchin.pdf

Center for Science in the Public Interest. Food Dyes: A Rainbow of Risks. CSPI, 2010 https://www.cspinet.org/resource/food-dyes-rainbow-risks

Chang AR et al., 2013. High dietary phosphorus intake is associated with all-cause mortality: results from NHANES III. Am J Clin Nutr. 2014 Feb; 99(2): 320–327. Published online 2013 Nov 13. https://pubmed.ncbi.nlm.nih.gov/24225358/

Chassaing et al. (2017). Dietary emulsifiers directly alter human microbiota composition and gene expression ex vivo potentiating intestinal inflammation. Gut, 66(8), 1414-1427. https://pubmed.ncbi.nlm.nih.gov/28325746/

Chassaing, B., Koren, O., Goodrich, J. et al. Dietary emulsifiers impact the mouse gut microbiota promoting colitis and metabolic syndrome. Nature 519, 92–96 (2015). https://doi.org/10.1038/nature14232

Chazelas E, Pierre F, Druesne-Pecollo N, et al. Nitrites and nitrates from food additives and natural sources and cancer risk: results from the NutriNet-Santé cohort. Int J Epidemiol. https://pubmed.ncbi.nlm.nih.gov/35303088/

Chazelas, E., Druesne-Pecollo, N., Esseddik, Y. et al. Exposure to food additive mixtures in 106,000 French adults from the NutriNet-Santé cohort. Sci Rep 11, 19680 (2021). https://doi.org/10.1038/s41598-021-98496-6

Chen, Y. C., Yeh, Y. C., Lin, Y. F., Au, H. K., Hsia, S. M., Chen, Y. H., & Hsieh, R. H. (2022). Aspartame Consumption, Mitochondrial Disorder-Induced Impaired Ovarian Function, and Infertility Risk. International journal of molecular sciences, 23(21), 12740. https://www.mdpi.com/1422-0067/23/21/12740

Chen, Z., Chen, G., Zhou, K., Zhang, P., Ren, X., & Mei, X. (2019). Toxicity of food sweetener-sodium cyclamate on osteoblasts cells. Biochemical and biophysical research communications, 508(2), 507-511. https://doi.org/10.1016/j.bbrc.2018.11.172

Chi, L.; Bian, X.; Gao, B.; Tu, P.; Lai, Y.; Ru, H.; Lu, K. Effects of the Artificial Sweetener Neotame on the Gut Microbiome and Fecal Metabolites in Mice. Molecules 2018, 23, 367. https://doi.org/10.3390/molecules23020367

Chiang, Y. F., Chen, H. Y., Lai, Y. H., Ali, M., Chen, Y. C., & Hsia, S. M. (2022). Consumption of Artificial Sweetener Acesulfame Potassium Increases Preterm Risk and Uterine Contraction with Calcium Influx Increased via Myosin Light Chain Kinase–Myosin Light Chain 20 Related Signaling Pathway. Molecular Nutrition & Food Research, 66(20), 2200298. https://doi.org/10.1002/mnfr.202200298

Chin-Chan, M.; Navarro-Yepes, J.; Quintanilla-Vega, B. Environmental Pollutants as Risk Factors for Neurodegenerative Disorders: Alzheimer and Parkinson Diseases. Front Cell Neurosci 2015, 9. https://pmc.ncbi.nlm.nih.gov/articles/PMC4392704/

Clemmensen, O., & Hjorth, N. (1982). Perioral contact urticaria from sorbic acid and benzoic acid in a salad dressing. Contact dermatitis, 8(1), 1-6.

Code of Federal regulations (2016). Mono- and diglycerides. https://www.ecfr.gov/current/title-21/chapter-I/subchapter-B/part-184/subpart-B/section-184.1505

Code of Federal Regulations (2024). Food Preservatives. https://www.ecfr.gov/current/title-21/chapter-I/subchapter-B/part-172/subpart-B

Cohen SM, Ito N. A critical review of the toxicological effects of carrageenan and processed eucheuma seaweed on the gastrointestinal tract. Crit Rev Toxicol. 2002 Sep;32(5):413-44. Review. https://pubmed.ncbi.nlm.nih.gov/12389870/

Commission Delegated Regulation (EU) 2024/2512 of 17 April 2024 amending Annex II to Regulation (EU) No 1169/2011 of the European Parliament and of the Council on the provision of food information to consumers, as regards behenic acid from mustard seeds to be used in the manufacturing of certain emulsifiers https://eur-lex.europa.eu/legal-content/EN/TXT/?uri=OJ%3AL_202402512

Commission Regulation (EU) No 231/2012 of 9 March 2012 laying down specifications for food additives listed in Annexes II and III to Regulation (EC) No 1333/2008 of the European Parliament and of the Council https://eur-lex.europa.eu/legal-content/EN/TXT/?uri=celex%3A32012R0231

Commission Regulation (EU) No 257/2010 of 25 March 2010 setting up a programme for the re-evaluation of approved food additives in accordance with Regulation (EC) No 1333/2008 of the European Parliament and of the Council on food additives https://eur-lex.europa.eu/legal-content/EN/ALL/?uri=CELEX%3A32010R0257

Commission Regulation (EU) No 380/2012 of 3 May 2012 amending Annex II to Regulation (EC) No 1333/2008 of the European Parliament and of the Council as regards the conditions of use and the use levels for aluminium-containing food additives https://eur-lex.europa.eu/legal-content/EN/ALL/?uri=celex%3A32012R0380

Cong, W. N., Wang, R., Cai, H., Daimon, C. M., Scheibye-Knudsen, M., Bohr, V. A., ... & Martin, B. (2013). Long-term artificial sweetener acesulfame potassium treatment alters neurometabolic functions in C57BL/6J mice. PLoS One, 8(8), e70257. https://doi.org/10.1371/journal.pone.0070257

Cornu, R., Chrétien, C., Pellequer, Y., Martin, H., & Béduneau, A. (2020). Small silica nanoparticles transiently modulate the intestinal permeability by actin cytoskeleton disruption in both Caco-2 and Caco-2/HT29-MTX models. Archives of Toxicology, 94(4), 1191-1202.

Crowe W, Elliott CT, Green BD. A Review of the In Vivo Evidence Investigating the Role of Nitrite Exposure from Processed Meat Consumption in the Development of Colorectal Cancer. Nutrients. 2019 Nov 5;11(11):2673. https://pubmed.ncbi.nlm.nih.gov/31694233/

Csáki, K. F. (2011). Synthetic surfactant food additives can cause intestinal barrier dysfunction. Medical hypotheses, 76(5), 676-681. https://pubmed.ncbi.nlm.nih.gov/21300443/

CSPCI, Color additive petition pursuant to 21 U.S.C. §§ 379e, 721(b)(1) to remove FD&C Red No. 3 from the permanent list of color additives approved for use in food and dietary supplements, 21 C.F.R. § 74.303, and for use in ingested drugs\n

CSPI, 2011. Petition to bar the use of caramel colorings produced with ammonia and containing certain carcinogens.

CSPI, 2012. Center for Science in the Public Interest. Lab tests find Carcinogen in regular diet coke and pepsi (CSPI)

CWG - Report CWG Additives 5 and 6 June 2024 - WGA 24/03/02 Use of additives on fresh fruit and vegetables (2020-7,16,18,19,20, 2021-03, 2022-2,3, 2023-4,5,6,7).\n https://www.row-minvws.nl/documenten/verslag/2024/06/05/verslag-cwg-additieven-5-en-6-juni-2024

Dai, X., Guo, Z., Chen, D., Li, L., Song, X., Liu, T., ... & Cao, H. (2020). Maternal sucralose intake alters gut microbiota of offspring and exacerbates hepatic steatosis in adulthood. Gut Microbes, 11(4), 1043-1063. https://pubmed.ncbi.nlm.nih.gov/32228300/

Darbre, P. D. Aluminium, Antiperspirants and Breast Cancer. J. Inorg. Biochem. 2005, 99 (9), 1912–1919.

Davalli et al., 2012. The potential role of glutamate in the current diabetes epidemic. Acta diabetologica, 49(3), 167-183.

de la Garza, A. L., Romero-Delgado, B., Martínez-Tamez, A. M., Cárdenas-Tueme, M., Camacho-Zamora, B. D., Matta-Yee-Chig, D., ... & Camacho-Morales, A. (2022). Maternal sweeteners intake modulates gut microbiota and exacerbates learning and memory processes in adult male offspring. Frontiers in Pediatrics, 1038. https://doi.org/10.3389/fped.2021.746437

Debras C, Chazelas E, Sellem L, Porcher R, Druesne-Pecollo N, Esseddik Y et al. Artificial sweeteners and risk of cardiovascular diseases: results from the prospective NutriNet-Santé cohort BMJ 2022; 378 :e071204. https://doi.org/10.1136/bmj-2022-071204

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EFSA (2021). Opinion on the re‐evaluation of mono‐ and diglycerides of fatty acids (E 471) as food additive in foods for infants below 16 weeks of age and follow‐up of their re‐evaluation as food additives for uses in foods for all population groups. https://www.efsa.europa.eu/en/efsajournal/pub/6885

EFSA ANS Panel (EFSA Panel on Food Additives and Nutrient Sources added to Food), Younes M, Aggett P, Aguilar F, Crebelli R, Dusemund B, Filipič M, Frutos MJ, Galtier P, Gott D, Gundert-Remy U, Kuhnle GG, Leblanc J-C, Lillegaard IT, Moldeus P, Mortensen A, Oskarsson A, Stankovic I, Waalkens-Berendsen I, Woutersen RA, Wright M, Boon P, Chrysafidis D, Gürtler R, Mosesso P, Parent-Massin D, Tobback P, Kovalkovicova N, Rincon AM, Tard A and Lambré C, 2018. Scientific Opinion on the re-evaluation of silicon dioxide (E 551) as a food additive. EFSA Journal 2018;16(1):5088, 70 pp. https://doi.org/10.2903/j.efsa.2018.5088

EFSA, 2004. Opinion of the Scientific Panel on Dietetic products, nutrition and allergies [NDA] on a request from the Commission relating to the evaluation of allergenic foods for labelling purposes. EFSA Journal 2004;32, 197 pp.

EFSA, 2004. Opinion of the Scientific Panel on food additives, flavourings, processing aids and materials in contact with food (AFC) on a request from the Commission related to tertiary-Butylhydroquinone (TBHQ). EFSA Journal (2004) 24, 1-13

EFSA, 2004. Opinion on sucrose esters of fatty acids E 473 and sucroglycerides E 474. The EFSA Journal, 106, 1-24. https://www.efsa.europa.eu/en/efsajournal/pub/106

EFSA, 2007. Beeswax (E 901) as a glazing agent and as carrier for flavours - Scientific Opinion of the Panel on Food additives, Flavourings, Processing aids and Materials in Contact with Food (AFC). https://www.efsa.europa.eu/fr/efsajournal/pub/615

EFSA, 2008. Assessment of the results of the study by McCann et al.(2007) on the effect of some colours and sodium benzoate on children's behaviour‐Scientific Opinion of the Panel on Food Additives, Flavourings, Processing Aids and Food Contact Materials (AFC). EFSA Journal, 6(3), 660. https://www.efsa.europa.eu/en/efsajournal/pub/660

EFSA, 2008. EFSA evaluates Southampton study on food additives and child behaviour. https://www.efsa.europa.eu/en/news/efsa-evaluates-southampton-study-food-additives-and-child-behaviour

EFSA, 2008. Safety of aluminium from dietary intake[1] - Scientific Opinion of the Panel on Food Additives, Flavourings, Processing Aids and Food Contact Materials (AFC). EFSA Journal (2008) 754, 1-34. https://www.efsa.europa.eu/en/efsajournal/pub/754

EFSA, 2009. EFSA Panel on Food Additives and Nutrient Sources added to Food (ANS); Scientific Opinion on the re-evaluation of Allura Red AC (E 129) as a food additive on request from the European Commission. EFSA Journal 2009; 7(11):1327. [39 pp.]. doi:10.2903/j.efsa.2009.1327. https://www.efsa.europa.eu/en/efsajournal/pub/1327

EFSA, 2009. Scientific Opinion of the Panel on Food Additives, Flavourings, Processing Aids and Materials in Contact with Food on a request from Commission on Flavouring Group Evaluation 46 (FGE.46). Ammonia and two ammonium salts from chemical group 30 (2009) https://www.efsa.europa.eu/fr/efsajournal/pub/955

EFSA, 2009. Scientific Opinion on the re‐evaluation Tartrazine (E 102). EFSA Journal, 7(11), 1331.

EFSA, 2009. Scientific Opinion on the use of natamycin (E 235) as a food additive. EFSA Journal 2009;7(12):1412

EFSA, 2010. EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA); Scientific Opinion on the appropriateness of the food azo-colours Tartrazine (E 102), Sunset Yellow FCF (E 110), Carmoisine (E 122), Amaranth (E 123), Ponceau 4R (E 124), Allura Red AC (E 129), Brilliant Black BN (E 151), Brown FK (E 154), Brown HT (E 155) and Litholrubine BK (E 180) for inclusion in the list of food ingredients set up in Annex IIIa of Directive 2000/13/EC. EFSA Journal 2010; 8(10):1778. [11 pp.]. doi:10.2903/j.efsa.2010.1778 https://efsa.onlinelibrary.wiley.com/doi/abs/10.2903/j.efsa.2010.1778

EFSA, 2010. Scientific Opinion on the appropriateness of the food azo-colours Tartrazine (E 102), Sunset Yellow FCF (E 110), Carmoisine (E 122), Amaranth (E 123), Ponceau 4R (E 124), Allura Red AC (E 129), Brilliant Black BN (E 151), Brown FK (E 154), Brown HT (E 155) and Litholrubine BK (E 180) for inclusion in the list of food ingredients set up in Annex IIIa of Directive 2000/13/EC. EFSA Journal, 8(10):1778.

EFSA, 2010. Scientific Opinion on the re‐evaluation of Brilliant Blue FCF (E 133) as a food additive. EFSA Journal, 8(11), 1853. https://www.efsa.europa.eu/en/efsajournal/pub/1853

EFSA, 2010. Scientific Opinion on the safety of sucrose esters of fatty acids prepared from vinyl esters of fatty acids and on the extension of use of sucrose esters of fatty acids in flavourings. EFSA Journal, 8(3), 1512. doi:10.2903/j.efsa.2010.1512 https://www.efsa.europa.eu/en/efsajournal/pub/1512

EFSA, 2010. Statement in relation to the safety of erythritol (E 968) in light of new data, including a new paediatric study on the gastrointestinal tolerability of erythritol. EFSA Journal, 8(7), 1650.

EFSA, 2011. EFSA Panel on Food Additives and Nutrient Sources added to Food (ANS); Scientific Opinion on the re-evaluation of Erythrosine (E 127) as a food additive. EFSA Journal 2011; 9(1):1854. [46 pp.]. \n https://efsa.onlinelibrary.wiley.com/doi/abs/10.2903/j.efsa.2011.1854

EFSA, 2011. European Food Safety Authority; Revised exposure assessment for Sunset Yellow FCF based on the proposed revised maximum permitted levels of use as a food additive. EFSA Journal 2011; 9(9):2349. [10 pp.] doi:10.2903/j.efsa.2011.2349. https://www.efsa.europa.eu/en/efsajournal/pub/2349

EFSA, 2011. Revised exposure assessment for steviol glycosides for the proposed uses as a food additive. EFSA Journal 2011;9(1):1972, 19 pp. doi:10.2903/j.efsa.2011.1972

EFSA, 2011. Scientific Opinion on Flavouring Group Evaluation 46, Revision 1 (FGE.46Rev1): Ammonia and three ammonium salts from chemical group 30. EFSA Journal 2011; 9(2):1925. [35 pp.]\n\n https://www.efsa.europa.eu/en/efsajournal/pub/1925

EFSA, 2011. Scientific Opinion on re-evaluation of calcium carbonate (E 170) as a food additive. EFSA Journal 2011;9(7):2318

EFSA, 2011. Scientific Opinion on the re‐evaluation of butylated hydroxyanisole–BHA (E 320) as a food additive. EFSA Journal, 9(10), 2392.

EFSA, 2011. Scientific Opinion on the re‐evaluation of caramel colours (E 150 a, b, c, d) as food additives. https://www.efsa.europa.eu/en/efsajournal/pub/2004

EFSA, 2011. Scientific Opinion on the substantiation of health claims related to the sugar replacers xylitol, sorbitol, mannitol, maltitol, lactitol, isomalt, erythritol, D‐tagatose, isomaltulose, sucralose and polydextrose and maintenance of tooth mineralisation by decreasing tooth demineralisation (ID 463, 464, 563, 618, 647, 1182, 1591, 2907, 2921, 4300), and reduction of post‐prandial glycaemic responses (ID 617, 619, 669, 1590, 1762, 2903, 2908, 2920) pursuant to Article 13 (1) of Regulation (EC) No 1924/2006. EFSA Journal, 9(4), 2076.

EFSA, 2012. European Food Safety Authority; Health risk of ammonium released from water filters. EFSA Journal https://efsa.onlinelibrary.wiley.com/doi/abs/10.2903/j.efsa.2012.2918

EFSA, 2012. Scientific Opinion on the safety and efficacy of ammonium chloride for bovines, sheep, dogs and cats. EFSA Journal 2012; 10(6):2738. [18 pp.] \n https://efsa.onlinelibrary.wiley.com/doi/abs/10.2903/j.efsa.2012.2738

EFSA, 2012. Refined exposure assessment for caramel colours (E 150a, c, d). EFSA Journal, 10(12), 3030.

EFSA, 2012. Scientific Opinion on the exposure assessment of sucrose esters of fatty acids (E 473) from its use as food additive. EFSA Journal, 10(5), 2658. doi:10.2903/j.efsa.2012.2658 https://www.efsa.europa.eu/en/efsajournal/pub/2658

EFSA, 2012. Scientific Opinion on the re‐evaluation of butylated hydroxytoluene BHT (E 321) as a food additive. EFSA Journal, 10(3), 2588. https://www.efsa.europa.eu/en/efsajournal/pub/2588

EFSA, 2012. Statement on the safety assessment of the exposure to butylated hydroxyanisole E 320 (BHA) by applying a new exposure assessment methodology. https://efsa.onlinelibrary.wiley.com/doi/epdf/10.2903/j.efsa.2012.2759

EFSA, 2013. EFSA Panel on Food Additives and Nutrient Sources added to Food (ANS); Scientific Opinion on the re-evaluation of Patent Blue V (E 131) as a food additive. EFSA Journal 2013; 11(3):2818. [35 pp.] doi:10.2903/j.efsa.2013.2818. https://www.efsa.europa.eu/en/efsajournal/pub/2818

EFSA, 2013. Scientific Opinion on the re-evaluation of aspartame (E 951) as a food additive. EFSA Journal 2013;11(12):3496. https://www.efsa.europa.eu/fr/efsajournal/pub/3496

EFSA, 2013. Scientific Opinion on the re-evaluation of sodium stearoyl-2-lactylate (E 481) and calcium stearoyl-2-lactylate (E 482) as food additives. EFSA Journal 2013;11(5):3144.

EFSA, 2013. Statement on the exposure assessment of sodium stearoyl-2-lactylate and calcium stearoyl-2-lactylate including exposure resulting from extension of the authorisation of sodium stearoyl-2-lactylates. EFSA Journal 2013;11(3):3125.

EFSA, 2014. EFSA ANS Panel (Panel on Food Additives and Nutrient Sources added to Food), 2014. Scientific opinion on the reconsideration of the temporary ADI and refined exposure assessment for Sunset Yellow FCF (E 110). EFSA Journal 2014; 12(7):3765, 39 pp. doi:10.2903/j.efsa.2014.3765 https://www.efsa.europa.eu/en/efsajournal/pub/3765

EFSA, 2014. Scientific Opinion on the re-evaluation of propionic acid (E 280), sodium propionate (E 281), calcium propionate (E 282) and potassium propionate (E 283) as food additives. EFSA Journal 2014;12(7):3779

EFSA, 2014. Scientific Opinion on the re-evaluation of propyl gallate (E 310) as a food additive. EFSA Journal 2014; 12(4):3642, 46 pp. doi:10.2903/j.efsa.2014.3642\n https://www.efsa.europa.eu/en/efsajournal/pub/3642

EFSA, 2014. Scientific Opinion on the revised exposure assessment of steviol glycosides (E 960) for the proposed uses as a food additive. EFSA Journal 2014;12(5):3639, 23 pp.

EFSA, 2015. European Food Safety Authority. (2015). Refined exposure assessment for Allura Red AC (E 129). EFSA Journal, 13(2), 4007. https://www.efsa.europa.eu/en/efsajournal/pub/4007

EFSA, 2015. Scientific Opinion on Dietary Reference Values for phosphorus. EFSA Journal 2015; 13( 7):4185, 54 pp.

EFSA, 2015. Scientific Opinion on the extension of use of steviol glycosides (E 960) as a food additive. EFSA Journal 2015;13(6):4146, 20 pp.

EFSA, 2015. Scientific Opinion on the re-evaluation of polyoxyethylene sorbitan monolaurate (E 432), polyoxyethylene sorbitan monooleate (E 433), polyoxyethylene sorbitan monopalmitate (E 434), polyoxyethylene sorbitan monostearate (E 435) and polyoxyethylene sorbitan tristearate (E 436) as food additives. EFSA Journal 2015;13(7):4152 https://www.efsa.europa.eu/en/efsajournal/pub/4152

EFSA, 2015. Scientific Opinion on the re‐evaluation of cochineal, carminic acid, carmines (E 120) as a food additive. EFSA Journal, 13(11), 4288.

EFSA, 2015. Scientific Opinion on the re‐evaluation of sorbic acid (E 200), potassium sorbate (E 202) and calcium sorbate (E 203) as food additives. EFSA Journal, 13(6), 4144.

EFSA, 2015. Scientific Opinion on the safety of the proposed extension of use of - erythritol (E 968) as a food additive.

EFSA, 2015. Update of the Scientific Opinion on the safety and efficacy of erythrosine in feed for cats, dogs, reptiles and ornamental fish. EFSA Journal 2015; 13 (9):4233, 19 pp https://efsa.onlinelibrary.wiley.com/doi/abs/10.2903/j.efsa.2015.4233

EFSA, 2016. Re-evaluation of titanium dioxide (E 171) as a food additive. https://efsa.onlinelibrary.wiley.com/doi/epdf/10.2903/j.efsa.2016.4545

EFSA, 2016. Safety of the extension of use of sodium propionate (E 281) as a food additive. EFSA Journal. 14.

EFSA, 2016. Scientific Opinion on erucic acid in feed and food. EFSA Journal 2016; 14(11):4593, 173 pp. doi:10.2903/j.efsa.2016.4593 https://www.efsa.europa.eu/en/efsajournal/pub/4593

EFSA, 2016. Scientific Opinion on the re-evaluation of sulfur dioxide (E 220), sodium sulfite (E 221), sodium bisulfite (E 222), sodium metabisulfite (E 223), potassium metabisulfite (E 224), calcium sulfite (E 226), calcium bisulfite (E 227) and potassium bisulfite (E 228) as food additives. EFSA Journal 2016; 14(4): 4438.

EFSA, 2016. Scientific Opinion on the re‐evaluation of benzoic acid (E 210), sodium benzoate (E 211), potassium benzoate (E 212) and calcium benzoate (E 213) as food additives. EFSA Journal, 14(3), 4433. https://www.efsa.europa.eu/en/efsajournal/pub/4433

EFSA, 2016. Scientific opinion on the risks for human health related to the presence of 3- and 2-monochloropropanediol (MCPD), and their fatty acid esters, and glycidyl fatty acid esters in food. EFSA J. 14, 159. https://doi.org/10.2903/j.efsa.2016.4426

EFSA, 2016. Statement on the refined exposure assessment of tertiary-butyl hydroquinone (E 319). EFSA Journal 2016;14(1):4363

EFSA, 2016. The safety of annatto extracts (E 160b) as a food additive. EFSA Journal 2016;14(8):4544

EFSA, 2017. Call for technical and toxicological data on sweeteners authorised as food additives in the EU.

EFSA, 2017. Exposure assessment of annatto colouring principles bixin and norbixin (E 160b) when used as food additives. EFSA Journal 2017;15(8):4966

EFSA, 2017. L'évaluation des risques expliquée par l’Efsa - Nitrites et nitrates ajoutés aux aliments. EFSA Journal 2017;15(6):4786. https://www.efsa.europa.eu/sites/default/files/corporate_publications/files/nitrates-nitrites-170614-FR.pdf

EFSA, 2017. Re-evaluation of potassium nitrite (E 249) and sodium nitrite (E 250) as food additives. EFSA Journal 2017;15(6):4786. https://www.efsa.europa.eu/en/efsajournal/pub/4786

EFSA, 2017. Re‐evaluation of glutamic acid (E 620), sodium glutamate (E 621), potassium glutamate (E 622), calcium glutamate (E 623), ammonium glutamate (E 624) and magnesium glutamate (E 625) as food additives. EFSA Journal, 15(7), e04910.

EFSA, 2017. Re‐evaluation of glycerol (E 422) as a food additive. EFSA Journal, 15(3), e04720 https://efsa.onlinelibrary.wiley.com/doi/epdf/10.2903/j.efsa.2017.4720

EFSA, 2017. Re‐evaluation of guar gum (E 412) as a food additive. https://www.efsa.europa.eu/en/efsajournal/pub/4669

EFSA, 2017. Re‐evaluation of mono‐and di‐glycerides of fatty acids (E 471) as food additives. EFSA Journal, 15(11), e05045. https://efsa.onlinelibrary.wiley.com/doi/10.2903/j.efsa.2017.5045

EFSA, 2017. Scientific Opinion on the re-evaluation of polyglycerol esters of fatty acids (E 475) as a food additive. EFSA Journal 2017;15(12):5089, 32 pp. https://doi.org/10.2903/j.efsa.2017.5089

EFSA, 2017. Scientific Opinion on the re-evaluation of sorbitan monostearate (E 491), sorbitan tristearate (E 492), sorbitan monolaurate (E 493), sorbitan monooleate (E 494) and sorbitan monopalmitate (E 495) when used as food additives. EFSA Journal 2017; 15(5):4788, 56 pp.\n https://doi.org/10.2903/j.efsa.2017.4788

EFSA, 2017. Statement on the validity of the conclusions of a mouse carcinogenicity study on sucralose (E 955) performed by the Ramazzini Institute. EFSA Journal 2017; 15( 5):4784, 14 pp. https://doi.org/10.2903/j.efsa.2017.4784

EFSA, 2018. Call for food additives usage level and / or concentration data in food and beverages intended for human consumption.

EFSA, 2018. Call for technical and toxicological data on sodium carboxymethylcellulose (E 466) for uses as a food additive in foods for all population groups including infants below 16 weeks of age

EFSA, 2018. Call for technical data on the permitted food additive glycerol (E422).

EFSA, 2018. Call for technological data on mono- and di-glycerides of fatty acids (E 471) for uses as a food additive in foods for all population groups including infants below 16 weeks of age https://www.efsa.europa.eu/en/consultations/call/call-technical-and-toxicological-data-mono-and-di-glycerides-fatty

EFSA, 2018. EFSA Scientific Committee, Hardy A, Benford D, Halldorsson T, Jeger MJ, Knutsen HK, More S, Naegeli H, Noteborn H, Ockleford C, Ricci A, Rychen G, Schlatter JR, Silano V, Solecki R, Turck D, Younes M, Chaudhry Q, Cubadda F, Gott D, Oomen A, Weigel S, Karamitrou M, Schoonjans R and Mortensen A, 2018. Guidance on risk assessment of the application of nanoscience and nanotechnologies in the food and feed chain: Part 1, human and animal health. EFSA Journal 2018;16(7):5327, 95 pp. https://doi.org/10.2903/j.efsa.2018.5327

EFSA, 2018. Re-evaluation of aluminium sulphates (E520–E523) and sodium aluminium phosphate (E541) as food additives. EFSA Journal 2018;16(7):5372.

EFSA, 2018. Re-evaluation of silicon dioxide (E 551) as a food additive. EFSA Journal 2018;16(1):5088

EFSA, 2018. Re‐evaluation of carrageenan (E 407) and processed Eucheuma seaweed (E 407a) as food additives. EFSA Journal, 16(4), e05238. https://www.efsa.europa.eu/en/efsajournal/pub/5238

EFSA, 2018. Re‐evaluation of celluloses E 460 (i), E 460 (ii), E 461, E 462, E 463, E 464, E 465, E 466, E 468 and E 469 as food additives. EFSA Journal, 16(1), e05047.

EFSA, 2018. Re‐evaluation of celluloses E 460(i), E 460(ii), E 461, E 462, E 463, E 464, E 465, E 466, E 468 and E 469 as food additives. https://www.efsa.europa.eu/en/efsajournal/pub/5047

EFSA, 2018. Re‐evaluation of sodium aluminium phosphate (E 541) as a food additive. EFSA Journal, 16(7), 5372. https://doi.org/10.2903/j.efsa.2018.5372

EFSA, 2018. Scientific Opinion on the re-evaluation of propane-1,2-diol (E 1520) as a food additive. EFSA Journal 2018;16(4):5235, 40 pp. https://doi.org/10.2903/j.efsa.2018.5235

EFSA, 2018. Scientific Opinion on the re-evaluation of propane-1,2-diol esters of fatty acids (E 477) as a food additive. EFSA Journal 2018;16(12):5497, 30 pp. https://doi.org/10.2903/j.efsa.2018.5497

EFSA, 2018. Scientific Opinion on the refined exposure assessment of sucrose esters of fatty acids (E 473) from its use as a food additive. EFSA Journal;16(1):5087, 22 pp. doi: 10.2903/j.efsa.2018.5087 https://www.efsa.europa.eu/en/efsajournal/pub/5087

EFSA, 2019. FAF Panel (EFSA Panel on Food Additives and Flavourings), Younes M, Aquilina G, Castle L, Engel K-H, Fowler P, Frutos Fernandez MJ, Fürst P, Gürtler R, Husøy T, Mennes W, Moldeus P, Oskarsson A, Shah R, Waalkens-Berendsen I, Wölfle D, Aggett P, Cupisti A, Fortes C, Kuhnle G, Lillegaard IT, Scotter M, Giarola A, Rincon A, Tard A and Gundert-Remy U, 2019. Scientific Opinion on the re-evaluation of phosphoric acid–phosphates – di-, tri- and polyphosphates (E 338–341, E 343, E 450–452) as food additives and the safety of proposed extension of use. EFSA Journal 2019;17(6):5674, 156 pp. https://doi.org/10.2903/j.efsa.2019.5674

EFSA, 2019. Opinion on the follow‐up of the re‐evaluation of sorbic acid (E200) and potassium sorbate (E202) as food additives. EFSA Journal, 17(3), e05625.

EFSA, 2019. Opinion on the re‐evaluation of acacia gum (E 414) as a food additive in foods for infants below 16 weeks of age and the follow‐up of its re‐evaluation as a food additive for uses in foods for all population groups. https://www.efsa.europa.eu/en/efsajournal/pub/5922

EFSA, 2019. Outcome of the questions for health professionals in the fields of nephrology, mineral metabolism, cardiovascular and nutrition medicine on phosphates food additives re-evaluation https://www.efsa.europa.eu/en/supporting/pub/en-1624

EFSA, 2019. Re-evaluation of sulphuric acid and its sodium, potassium, calcium and ammonium salts (E 513, 514 (i), 514 (ii), 515 (i), 515 (ii), 516 and 517) as food additive. EFSA Journal 2019;17(10):5868

EFSA, 2019. Safety of annatto E and the exposure to the annatto colouring principles bixin and norbixin (E 160b) when used as a food additive. EFSA Journal 2019;17(3):5626

EFSA, 2019. Updated Re-evaluation of food additives : tentative work programme 2019 https://www.efsa.europa.eu/sites/default/files/foodaddtentativewp19.pdf

EFSA, 2020. Scientific Opinion on the safety and efficacy of propyl gallate for all animal species. EFSA Journal 2020;18(4):6069, 16 pp. https://doi.org/10.2903/j.efsa.2020.6069

EFSA, 2021. EFSA Scientific Committee, More S, Bampidis V, Benford D, Bragard C, Halldorsson T, Hernández-Jerez A, Bennekou SH, Koutsoumanis K, Lambré C, Machera K, Naegeli H, Nielsen S, Schlatter J, Schrenk D, Silano (deceased) V, Turck D, Younes M, Castenmiller J, Chaudhry Q, Cubadda F, Franz R, Gott D, Mast J, Mortensen A, Oomen AG, Weigel S, Barthelemy E, Rincon A, Tarazona J and Schoonjans R, 2021. Guidance on technical requirements for regulated food and feed product applications to establish the presence of small particles including nanoparticles. EFSA Journal 2021;19(8):6769, 48 pp. https://doi.org/10.2903/j.efsa.2021.6769

EFSA, 2021. EFSA Scientific Committee, More S, Bampidis V, Benford D, Bragard C, Halldorsson T, Hernández-Jerez A, Hougaard Bennekou S, Koutsoumanis K, Lambré C, Machera K, Naegeli H, Nielsen S, Schlatter J, Schrenk D, Silano V, Turck D, Younes M, Castenmiller J, Chaudhry Q, Cubadda F, Franz R, Gott D, Mast J, Mortensen A, Oomen AG, Weigel S, Barthelemy E, Rincon A, Tarazona J and Schoonjans R 2021. Guidance on risk assessment of nanomaterials to be applied in the food and feed chain: human and animal health. EFSA Journal 2021;19(8):6768, 111 pp. https://doi.org/10.2903/j.efsa.2021.6768

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